Abstract
See related article, p 1046. The diagnosis of chronic fatigue is largely based on exclusion of other conditions, shows frequent comorbidities, has no known neuropathological basis, and no confirmed single etiology, pathogenesis or established treatment. It is not easily accepted by patients and caregivers alike, and probably the most effective remedy up to now has been to find patients with similar conditions to share experiences. Chronic fatigue is an accepted medical term, especially when presenting in chronic multiple sclerosis or other mostly postviral conditions. In these patients, cognitive behavior therapy and graded exercise therapy have recently been shown to moderately improve outcome.1 In stroke patients, however, fatigue has not been clearly defined, and interventions tested in these populations have only been based on very small numbers. In one review, poststroke fatigue has been described as “a feeling of early exhaustion developing during mental activity with weariness, lack of energy, and aversion to effort.”2 However, the most striking feature of chronic fatigue is that it is always present. It does not go away …
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