Abstract
Background. Postpartum acute kidney injury is a serious obstetric complication, and its diagnostic definition is highly variable in the literature. Recent studies reported an incidence up to 40% in both developed and developing countries. PP-AKI is associated with an increased risk of chronic kidney disease, and cardiovascular disease. Methods. We conducted a single center case control study for PP-AKI cases. Forty six women were recruited in the study, and they represented two groups, PP-AKI group (n=18), and healthy control group (n=38). Clinical examinations and laboratory investigations were collected. Results. Hypertension and CKD were reported in 5(27.8%), and 3(16.7%) of the included women in PP-AKI group respectively, while none of healthy control women had HTN, or CKD. PP-AKI patients exhibited significantly lower mean values for blood hemoglobin levels (7.9±1.36 g/dl), platelets counts (157.9±92.3×103/mm3), and serum albumin levels (2.9±0.4 gm/dl) in comparison with healthy controls. Additionally, PP-AKI patients exhibited significantly higher mean value for serum creatinine levels (5.3±2.9 mg/dl), and higher median and range values for prothrombin time 1(1-2.7) in comparison with healthy controls. Preeclampsia was the main possible etiology of PP-AKI.
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