Abstract
Concerns exist about the optimal analgesic for postoperative pain management following (adeno)tonsillectomy. Hence, we decided to review the efficacy of paracetamol (acetaminophen) and diclofenac in children aged 3 to 12 years after (adeno)tonsillectomy Pharmacokinetics and adverse effects of the two agents were also addressed. A MEDLINE search (1966 to 1998), review articles and textbooks were used as data sources. In general, systematic and practice-based research on these drugs for this indication is scarce. Paracetamol 20 mg/kg administered orally, 60 minutes preoperatively, and diclofenac 2 mg/kg administered rectally at induction seem to achieve satisfactory analgesia in the majority of children during the first few hours postoperatively.
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