Abstract
Background: Oxaliplatin-based hyperthermic intraperitoneal chemotherapy (HIPEC) to cytoreduction surgery (CRS) in peritoneal metastasis (PM) of colorectal origin did not show any survival benefit in PRODIGE-7 trial and additional value of other regimen-based HIPEC is under debate. However, centralization has been shown to improve post-operative mortality (POM) in CRS and HIPEC for PM of various origins. We aimed to evaluate the impact of centralization on POM after CRS alone.
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