Abstract
Introduction: Compensatory mechanisms resulting from the phenomenon of neuroplasticity are present in patients with neuroepithelial tumors, such as lowgrade gliomas (LGG). In the case of tumors located in the primary motor cortex, neural reorganization of motor activity to other areas of the brain may favor the maintenance of motor activity and avoid neurological deficits. Thus, this study sought to assess the movement of motor activity in patients with LGG. Materials and Methods: The search strategy used medical subject headings and text words related to neuroplasticity, LGG, and primary motor cortex. The PubMed and Biblioteca Virtual em Saúde databases were used. The search of articles was conducted from November 2020 to January 2021, and there was no time limit regarding article eligibility. Results: Four studies were included following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The contralateral motor and supplementary areas were the most active areas reported in the postoperative period. Given that this was a retrospective study, it did not demonstrate migration of motor activity, making surgical resection unfeasible. Conclusion: Knowing where motor function migration frequently occurs in patients with LGG is useful to optimize the resection of these tumors without inducing neurological deficits, thereby increasing the quality of resection in critical areas, such as the primary motor cortex.
Highlights
Capsaicin is able to induce mast cell degranulation, an event probably related to the pathophysiology of a migraine attack
The present review study aimed to address the mechanisms of action of capsaicin and other chemical inducers in mast cell degranulation and an interaction of nerves and events that happen in the dura mater with the activation of mast cells
Conclusion: the analyzed data indicate that the polymorphisms contributed to the susceptibility to Parkinson’s disease (PD), further studies related to the polymorphisms and their relationship to PD are still needed for more ethnic groups, and early diagnosis is possible
Summary
Capsaicin is able to induce mast cell degranulation, an event probably related to the pathophysiology of a migraine attack. Methods: A literature review and an observational, descriptive and transversal data collect on treatment for acute demyelinating polyradiculoneuritis, available at DATASUS from January 2008 to December 2020, and articles available at Scielo and PubMed. Results: There were 7,917 hospitalizations, representing a total expenditure of R$ 9,392,552.04, 2009 being the year with the highest number of hospitalizations (809) and 2017 with the highest amount spent during the period (R$ 967,284.65). Methods: A literature review and an observational, descriptive and transversal data collect on surgical treatment was carried out, available from January 2008 to December 2020 and articles available in Scielo, Lilacs and PubMed. Results: There were 15,148 hospitalizations for surgical procedures for the treatment of chronic subdural hematoma, representing a total expenditure of R$ 45,365,258.21, with 2018 being the year with the highest number of hospitalizations (1,418) and with the highest amount spent during the period (R$ 4,570,334.28). Conclusions: The “Coca-Cola Bottle sign” is a classic sign of Graves’ disease, some signs, such as, unilateral and single orbital musculature involvement, may be suggestive of involvement by other etiologies, suggesting the benefit of an early expanded investigation
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