Abstract
Postoperative fungal endophthalmitis is a rare but devastating complication of cataract surgery. Vitrectomy and intravitreal amphotericin B injection as well as administration of systemic antifungal agents have been suggested as optimal treatments for fungal endophthalmitis. However, this therapy may fail to eliminate fungal species resistant to current antifungal agents. The saprophytic fungus Trichosporon asahii is frequently observed as a cause of endogenous endophthalmitis in immunosuppressed patients. We report a case of postoperative endophthalmitis caused by T. asahii, resistant to amphotericin B. To the best of our knowledge, this is the first report of T. asahii endophthalmitis successfully treated with intravitreal and systemic voriconazole, pars plana vitrectomy, and removal of the intraocular lens and entire lens capsule.
Highlights
Trichosporon are saprophytic fungal species, which very rarely cause exogenous endophthalmitis and are possibly resistant to traditional antifungal therapy
We present a case of postoperative endophthalmitis caused by amphotericin B-resistant Trichosporon asahii
Trichosporon species, formerly known as Trichosporon beigelii, rarely cause exogenous endophthalmitis and comprise a number of genetically distinct species that are pathogenic to humans[1,3,4]
Summary
Trichosporon are saprophytic fungal species, which very rarely cause exogenous endophthalmitis and are possibly resistant to traditional antifungal therapy. Several endophthalmitis cases caused by Trichosporon species have been reported as a complication of fungemia in immunosuppressed patients and in one postoperative case[1,2]. We present a case of postoperative endophthalmitis caused by amphotericin B-resistant Trichosporon asahii. To the best of our knowledge, this is the first report of T. asahii endophthalmitis success fully treated with intravitreal and systemic voriconazole
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
