Abstract

Benign Prostatic Hyperplasia (BPH) is an enlarged prostate disease benign or a condition when the cells are present the prostate gland has an increased proliferation rate. There are several treatment options, including conservative (watchful waiting), medical, and surgery. Antibiotics in BPH cases can be prophylactic antibiotics or empiric antibiotics. This study was an observational study. The samples were BPH patients who received antibiotics for period January - November 2019. The pattern of prophylactic antibiotic use shows that most of the patients received ceftriaxone therapy. Operation on BPH patients is TURP which is an operation classified into surgery with a clean-contaminated category so that prophylactic antibiotics are required. There are two patterns of use for empiric antibiotics in BPH patients: single (88%) and combination (12%). The pattern of single or combined use is given to patients depending on the complications of the disease and the patient's clinical condition. BPH cases occur in men mostly occurs at the age of 60-74 years. Prophylactic antibiotic therapy in BPH patients, namely ceftriaxone 1 gr IV once daily was 48 patients (90.6%), a broad spectrum. Meanwhile, the most use of empirical antibiotics with a single pattern is Ceftriaxone 1 gr IV twice daily (35.6%).

Highlights

  • The prostate is a heart-shaped, solid and round male genital organ positioned between the bladder neck and the urogenital diaphragm

  • Benign prostatic hyperplasia (BPH) cases occur in men mostly occurs at the age of 60-74 years

  • The prostate will gradually increase in size and lead to BPH at more than 60 years old

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Summary

Introduction

The prostate is a heart-shaped, solid and round male genital organ positioned between the bladder neck and the urogenital diaphragm. Benign prostatic hyperplasia (BPH) is an enlarged prostate disease benign or a condition when the cells are present the prostate gland has an increased proliferation rate (Montorsi & Mercadante, 2013). BPH is characterized by changes in stromal cells and a persistent epithelium proliferation around the urethra, causing Lower Urinary Tract Symptoms (LUTS) (Leibbrand et al, 2019). A man who experiences LUTS begins to appear when a person has passed 50 years old (Montorsi & Mercadante, 2013). Data from Crimpen and the Baltimore Longitudinal Study of Aging (BLSA) show that prostate volume increases by 2.0% - 2.5% per year in advancing age. BPH continues to increase linearly up to 70 - 80% at age > 80 years old (Madersbacher, Sampson & Culig, 2019)

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