Postoperatif Radyoterapi Sonrası Alt Üriner Sistem Semptomlarının Değerlendirilmesinde Ürodinaminin Rolü: Retrospektif Kesitsel Çalışma

Abstract

Objective: The aim of this study was to evaluate lower urinary tract symptoms (LUTS) and urodynamic parameters in patients with prostate cancer who received adjuvant radiotherapy (ART) or salvage radiotherapy (SRT) following open radical prostatectomy (RP) or robot-assisted radical prostatectomy (RARP) by using urodynamic parameters. Material and Meth ods: Patients who were treated with ART or SRT following RP or RARP due to prostate cancer were included. International Consultation on Incon tinence Questionnaire-Urinary Incontinence Short Form (ICIQ-SF) and Inter national Prostate Symptom Score (IPSS) questionnaires were filled in for the evaluation of LUTS for each irradiated patient. Urodynamic parameters such as bladder pressure, maxi mum cystometric capacity, maximum urethral pressure, maximum urethral clo sure pressure used for diagnosis of intrinsic sphincteric deficiency (ISD), and urethral length were recorded. Results: Fifty patients had un dergone open RP, while 48 had undergone RARP. ART and SRT was applied with 55 and 43 patients, respectively.There was no significant difference between the groups in terms of IPSS and ICIQ-SF scores, urgency-related measurements and maximum cystometric capacity values. Findings in filling cystometry were not significant in comparison of both RP and radiotherapy technique (p>0.05). Maximum urethral closure pressure values were significantly higher in RARP recipients, the frequency of ISD was significantly higher in the open RP group, and ure thral length was longer in the RARP group. Conclusion: No significant differ ence was found in terms of LUTS in patients who underwent ART or SRT after RP. RARP had positive effects on functional urethral length, urethral clo sure pressures and ISD frequency, regardless of timing of radiotherapy.