Abstract
Within the scope of this technical report, the feasibility of indocyanine green (ICG) as a fluorescent agent for postmortem angiography of the heart is tested. The study included 4 deceased persons with no respective medical history of heart diseases. The basic patterns of findings in ICG fluorescence angiography associated with healthy hearts are presented. The method can easily be integrated into a workflow without restricting the macroscopic or histologic diagnostics. This paper represents the fundamental technical and analytical basis for upcoming studies concerning the possibilities and limitations of fluorescence angiography in the diagnosis of heart pathology.
Highlights
The basis of postmortem examination of cardiac pathology is represented by the combination of macroscopic and microscopic evaluation
Postmortem visualization of the vascular system of the heart has been subject to medical research in the past [1,2,3,4]
Newer studies primarily focus on the use of postmortem computed tomography in combination with contrast agents [6, 7]
Summary
The basis of postmortem examination of cardiac pathology is represented by the combination of macroscopic and microscopic evaluation. Using contrast agents to visualize the course of coronary arteries might give insights into pathologic mechanisms concerning coronary blood flow; the chosen method must not impair macroscopic or histologic evaluation. Postmortem visualization of the vascular system of the heart has been subject to medical research in the past [1,2,3,4]. In 1928, Campbell examined coronary circulation using barium injections [5]. Newer studies primarily focus on the use of postmortem computed tomography in combination with contrast agents [6, 7]. Thermography has been presented as a feasible method preserving the myocardial structure [8]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
