Postmenopausal Alopecia due to Ovarian Hyperandrogenemia Treated with Bilateral Salpingo-oophorectomy

Santanu Acharya,Srirupa Chakravorty,David Rae

doi:10.5005/jp-journals-10006-1771

Santanu Acharya, Srirupa Chakravorty + Show 1 more

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https://doi.org/10.5005/jp-journals-10006-1771

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Abstract

ABSTRACT Introduction Increased ovarian production of androgens due to the stimulation of luteinizing hormone (LH) on theca cells can cause hyperandrogenism that may present with signs of alopecia in postmenopausal women. Case description A 65-year-old postmenopausal woman presented to the gynecology clinic with male-pattern baldness. Serum testosterone was high that was suppressed with gonadotropin-releasing hormone analog (GnRH agonist). This confirmed ovarian source of androgens. Laparoscopic salpingo-oophorectomy helped reduce androgen levels over a period of an year therefore reversing at least partially the hair loss. Conclusion Gonadotropin-releasing hormone analogs can be useful to diagnose the source of increased androgen levels to be of ovarian origin. Once confirmed, laparoscopic bilateral salpingo-oophorectomy can reverse hair loss in these cases. How to cite this article Acharya S, Chakravorty S, Rae D. Postmenopausal Alopecia due to Ovarian Hyperandrogenemia Treated with Bilateral Salpingo-oophorectomy. J South Asian Feder Obst Gynae 2020;12(3):182–183.

Highlights

IntroductionIncreased ovarian production of androgens due to the stimulation of luteinizing hormone (LH) on theca cells can cause hyperandrogenism that may present with signs of alopecia in postmenopausal women
Increased ovarian production of androgens due to the stimulation of luteinizing hormone (LH) on theca cells can cause hyperandrogenism that may present with signs of alopecia in postmenopausal women.Case description: A 65-year-old postmenopausal woman presented to the gynecology clinic with male-pattern baldness
Gonadotropin-releasing hormone analogs can be useful to diagnose the source of increased androgen levels to be of ovarian origin

Summary

Introduction

Increased ovarian production of androgens due to the stimulation of luteinizing hormone (LH) on theca cells can cause hyperandrogenism that may present with signs of alopecia in postmenopausal women. Case description: A 65-year-old postmenopausal woman presented to the gynecology clinic with male-pattern baldness. Serum testosterone was high that was suppressed with gonadotropin-releasing hormone analog (GnRH agonist). Laparoscopic salpingo-oophorectomy helped reduce androgen levels over a period of an year reversing at least partially the hair loss

Conclusion

Operative Findings

Discussion