Post-genomics of Neisseria meningitidis: an update

Abstract

The following article is a correction to a previously published version: Bernardini G, Braconi D, Lusini P, Santucci A. Postgenomics of Neisseria meningitidis: an update. Expert Rev. Proteomics 6(2), 135–143 (2009). These corrections were made owing to concerns being raised regarding similarity between sections of the text with previously published works.For clarity, the corrected article is published in full below. The sections in bold text correspond to the corrected sections and are therefore different to the previously published version.Neisseria meningitidis infection still remains a major life-threatening bacterial disease worldwide. The availability of bacterial genomic sequences generated a paradigm shift in microbiological and vaccines sciences, and post-genomics (comparative genomics, functional genomics, proteomics and a combination/evolution of these techniques) played important roles in elucidating bacterial biological complexity and pathogenic traits, at the same time accelerating the development of therapeutic drugs and vaccines. This article summarizes the most recent technological and scientific advances in meningococcal biology and pathogenesis aimed at the development and characterization of vaccines against the pathogenic meningococci.