Abstract
The purpose of this study was to determine the relationship between a posterior vitreous detachment (PVD) and retinoschisis (RS) in 73 highly myopic (HM) young patients age 16.4 ± 6.9 years and 24 non-HM children age 8.4 ± 1.5 years. The presence of the paravascular retinal abnormalities was determined in the images obtained by a ultra-widefield OCT (UWF OCT) instrument with an image field of 23 × 20 mm. The results showed that a partial PVD was detected in 15 (21%) of the HM patients, and the number increased significantly with increasing age (P = 0.02). PVDs of any type were not found in the non-HM eyes. The number of microvascular folds also increased with age in the HM patients (P = 0.03). Medium-reflective columnar tissues were present between the detached vitreous and inner retinal surface in 4 (5%) eyes of the HM patients. Myopic RS was found in 3 (4%) HM patients in the paravascular area but not in the macular area. These results suggest that early partial PVD may play a role in pathological and proliferative vitreous changes of HM eyes. An intense vitreoretinal traction with bridging tissues may cause the various paravascular retinal abnormalities. In HM eyes, paravascular RS is already present at an early age which may progress to macular RS with aging.
Highlights
The purpose of this study was to determine the relationship between a posterior vitreous detachment (PVD) and retinoschisis (RS) in 73 highly myopic (HM) young patients age 16.4 ± 6.9 years and 24 non-HM children age 8.4 ± 1.5 years
We have been able to examine the vitreal changes of HM eyes of elderly patients, and it was noted that the presence of paravascular vitreal adhesions were important for the development of myopic macular retinoschisis (RS)[9]
73 eyes of 73 HM patients and 24 eyes of 24 non-HM patients who met the criteria for inclusion were studied
Summary
The purpose of this study was to determine the relationship between a posterior vitreous detachment (PVD) and retinoschisis (RS) in 73 highly myopic (HM) young patients age 16.4 ± 6.9 years and 24 non-HM children age 8.4 ± 1.5 years. Myopic RS was found in 3 (4%) HM patients in the paravascular area but not in the macular area These results suggest that early partial PVD may play a role in pathological and proliferative vitreous changes of HM eyes. Ultra-widefield OCT (UWF OCT) is a swept source OCT (SS OCT) device equipped with high refractive index lens which enables clinicians to examine the posterior vitreous in a wide and deep space[8] With this device, we have been able to examine the vitreal changes of HM eyes of elderly patients, and it was noted that the presence of paravascular vitreal adhesions were important for the development of myopic macular retinoschisis (RS)[9]. The incidence of PVD and paravascular abnormalities, and the effect of aging were investigated in young HM patients
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