Abstract

PurposeThis study aims to report a novel finding of posterior subhyaloid precipitates (PSPs) in two patients with cytomegalovirus (CMV) retinitis.MethodsA small case series was conducted.ResultsClinical findings, treatment, and follow-up of two patients with CMV and PSPs are presented.ConclusionsInflammatory precipitates may collect in the posterior subhyaloid space in acute CMV retinitis and resolve with treatment.

Highlights

  • This study aims to report a novel finding of posterior subhyaloid precipitates (PSPs) in two patients with cytomegalovirus (CMV) retinitis

  • We describe two patients in whom a novel finding of posterior subhyaloid precipitates (PSPs) was documented with fundus photography and spectral-domain optical coherence tomography (OCT)

  • Fundus examination of the left eye revealed a large 7×4 disk diameter (DD) irregular lesion superonasal to the optic nerve consisting of retinal whitening with granular appearance and characteristic isolated “satellite” lesions along its edge

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Summary

Introduction

This study aims to report a novel finding of posterior subhyaloid precipitates (PSPs) in two patients with cytomegalovirus (CMV) retinitis. The AIDS epidemic has provided an opportunity to study the course and clinical features of cytomegalovirus (CMV) retinitis, which is a leading cause of blindness in these immunocompromised patients. Anterior chamber inflammatory reactions are almost invariably present in a patient with active CMV retinitis, but moderate to severe intraocular inflammation is uncommon [4]. We describe two patients in whom a novel finding of posterior subhyaloid precipitates (PSPs) was documented with fundus photography and spectral-domain optical coherence tomography (OCT).

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