Abstract

Posterior Reversible Encephalopathy Syndrome (PRES) is a clinicoradiological syndrome of reversible subcortical vasogenic brain oedema that can arise in the setting of renal failure, cytotoxic drugs, autoimmune disorders, (pre)eclampsia or blood pressure fluctuations. An insufficient cerebral blood pressure autoregulatory response with disruption of the blood-brain barrier is a leading theory of the pathophysiological changes underlying PRES1. Multiple System Atrophy (MSA) is a neurodegenerative disorder characterized by a combination of parkinsonism, cerebellar, pyramidal and autonomic signs. The consequence of the latter is often blood pressure variations with clinically invalidating orthostatic hypotension. This article is protected by copyright. All rights reserved.

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