Abstract
BackgroundTo compare the influence of posterior capsule opacification (PCO) morphology and severity on intraocular stray light and visual function with different levels of contrast.MethodsForty-five patients diagnosed with PCO were included in this prospective consecutive case series. The Optical Quality Analysis System II (OQAS II) was adopted to assess the objective visual function including objective scatter index (OSI) and optical quality analysis system values (OVs) with 100, 20, and 9% contrast. RTVue-100 OCT was used to evaluate the PCO morphology and severity. Comparisons among visual function, morphology, and severity between pear type and fibrosis PCO were performed. The correlations among the PCO morphology, severity, OSI, and OVs were also determined.ResultsThere was a significant correlation between increased OSI and decreased visual acuity in PCO patients before laser capsulotomy. The changes of OSI were also correlated with the PCO area for the 3 mm IOL optic region (r = 0.43, p = 0.02). The OSI was significantly higher in pear type PCO when compared with fibrosis PCO (Z = − 4.06, p ≤ 0.001). In addition, the increased OSI in pear type PCO was significantly correlated with the 100% OVs and the 20% OVs but not with the 9% OVs. In fibrosis PCO, OSI was only correlated with the 100% OVs and the 20% OVs pre-YAG.ConclusionsOSI and OVs could objectively indicate the visual function impairment in PCO patients. Effects of PCO on light scattering and on objective visual function might be explained by the variations of morphology and severity.
Highlights
To compare the influence of posterior capsule opacification (PCO) morphology and severity on intraocular stray light and visual function with different levels of contrast
The Optical Quality Analysis System II (OQAS II) based on the double-pass technique has enabled the objective evaluation of the visual system, including the
The pre-YAG LogMAR visual acuity (VA) was correlated with the objective scatter index (OSI) as described in Fig. 2c, and the correlation coefficient was 0.49 (p = 0.001)
Summary
To compare the influence of posterior capsule opacification (PCO) morphology and severity on intraocular stray light and visual function with different levels of contrast. Posterior capsule opacification is still the major complication after cataract surgery, which impairs the visual function of 28% of patients 5 years after IOL implantation [1]. The most common method, has been used to remove the opacification of the posterior capsule. The decision to perform laser capsulotomy surgery commonly involves decreased visual acuity and visual disturbances. C-quant was used to assess the forward light scatter. This approach was based on the subjective compensation comparison method [5,6,7] and was patient-dependent and time consuming [8]. The Optical Quality Analysis System II (OQAS II) based on the double-pass technique has enabled the objective evaluation of the visual system, including the
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