Abstract
Introduction: It has been reported that the prevalence of Sleep Apnea Syndrome (SAS) in elderly people (over 65) is more than 20%. Elderly patients with SAS have a predilection to develop hypertension, arrhythmia, angina pectoris, myocardial infarction, diabetes mellitus, and cognitive decline. On the other hand, it is controversial that consumption of soy isoflavones, which are predominantly derived from soybeans, reduces the risk of cardiovascular disease. Recent study reveals, equol, a metabolite of an isoflavone, differs greatly among individuals. Equol is converted from daizein by specific gut bacteria, and is more bioavailable than soy isoflavone. In this study, we sought to confirm whether equol production status is associated with incidence of SAS.
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