Abstract
Objective: To document the clinical efficacy and safety of repeated injections of high botulinum toxin type A (BTX-A) dose (>800U per treatment session) in poststroke spastic hypertonia. Design: Retrospective. Setting: 2 spasticity clinics affiliated with 2 major medical schools. Participants: Stroke survivors with functionally limiting spastic hypertonia. Intervention: BTX-A (Botox) injections to hypertonic upper- and/or lower-limb muscles. Main Outcome Measures: Ashworth Scale for muscle tone and symptom checklist for adverse events.
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