Abstract
Objective: To determine whether there is an association between body mass index (BMI) earlier in life and/or Sillence type and age of onset of significant scoliosis in children with osteogenesis imperfecta (OI). Design: Retrospective analysis of a convenience sample. Setting: Biomedical research hospital. Participants:86 children with type III and IV OI enrolled in research protocols. 34 subjects met criteria for analysis. Subjects included ambulatory and nonambulatory children. Interventions: Not applicable.
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