Abstract
Summary. Two women with post‐transfusion purpura (PTP) are presented, one with anti‐HPA1a and the other with anti‐HPA3a antibodies. Platelet‐specific antibodies were identified using the platelet immunofluorescence test (PIFT) and the monoclonal antibody immobilization of platelet antigens (MAIPA) assay. Lymphocytotoxic and red cell antibodies were also detected in both patients, the latter being responsible for a delayed haemolytic transfusion reaction (DHTR). In the patient with anti‐HPA1a antibody, red cell anti‐c alloantibody was found in the serum and in the eluate from red cells; it was active in the monocyte monolayer assay (MMA). The patient with anti‐HPA3a antibody had the red cell alloantibodies anti‐D, ‐M and ‐S detected in the serum, the last being responsible for DHTR.
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