Abstract
Involuntary abnormal movements have been reported after ischaemic and haemorrhagic stroke. Post stroke movement disorders can appear as acute or delayed sequel. At the moment, for many of these disorders the knowledge of pharmacological treatment is still inadequate. Dopaminergic and GABAergic systems may be mainly involved in post-stroke movement disorders. This article provides a review on drugs commonly used in post-stroke movement disorders, given that some post-stroke movement disorders have shown a partial benefit with pharmacological approach.
Highlights
Movement disorders represent a documented complication of stroke; both hyperkinetic and hypokinetic movement disorders have been explained after ischaemic and haemorrhagic stroke [1,2]
This review aims to delineate the efficacy and safety of drugs used in the treatment of post-stroke movement disorders
Most are caused by lesions in the basal ganglia or thalamus but can occur with strokes at many different locations in the motor circuit
Summary
Movement disorders represent a documented complication of stroke; both hyperkinetic and hypokinetic movement disorders have been explained after ischaemic and haemorrhagic stroke [1,2]. One study which included 1,500 stroke patients, showed that 3.7% of these patients developed movement disorders [9], while Ghika-Schmid et al [10], described a prevalence of movement disorders in 1% of post stroke patients and an incidence of 0.08%. In both studies hemichorea was the most common movement disorder [9,10]
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