Abstract

ObjectiveTo explore the diagnostic value of digital subtraction angiography (DSA) and the effectiveness of endovascular treatment for a post-pancreaticoduodenectomy hemorrhage (PPH).ResultsDuring the DSA examination, positive results were found in 29 patients, yielding a positive rate of 69.0%. The manifestations of the DSA examination included contrast medium extravasation, pseudoaneurysm, and artery walls coarse. All 29 patients with positive results underwent endovascular treatment, including transartery embolization (TAE) in 28 patients and covered stents placement in one patient. The technical success and clinical success rates were 100% and 72.4%, respectively. Re-bleeding occurred in 8 of the 29 patients after the first treatment (27.6%). The mortality of PPH was 17.2% (5 of 29). Two of the five PPH patients died following severe infections, and three died from multiple organ failure.Materials and MethodsA DSA examination was conducted using clinical and imaging data of 42 patients, and endovascular treatment for delayed PPH was retrospectively analyzed.ConclusionsDSA examination is a minimally invasive and rapid method for the diagnosis of delayed PPH. For patients with positive DSA results, endovascular treatment can be performed rapidly, safely, and effectively. Therefore, the DSA examination and endovascular treatment could be considered a preferred treatment approach for delayed PPH.

Highlights

  • A pancreaticoduodenectomy (PD) is a classic method of operation in the field of abdominal surgery

  • During the digital subtraction angiography (DSA) examination, positive results were found in 29 patients, yielding a positive rate of 69.0%

  • Endoscopy therapy is used for early upper digestive tract mild hemorrhages; angiography interventions or surgical treatments will always be required for delayed hemorrhages

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Summary

Introduction

A pancreaticoduodenectomy (PD) is a classic method of operation in the field of abdominal surgery. Based on the time of occurrence, PPH can be classified as an early hemorrhage, which is frequently a result of technical failure and a delayed hemorrhage that may stem from an ulcer, pseudoaneurysm, eroded vessel, or anastomotic leakage. Endoscopy therapy is used for early upper digestive tract mild hemorrhages; angiography interventions or surgical treatments will always be required for delayed hemorrhages. Digital subtraction angiography (DSA) and endovascular treatment are the first choice for the diagnosis and therapy of delayed PPH [4, 5]. The aim was to evaluate the www.impactjournals.com/oncotarget diagnostic value of DSA as well as the safety, efficacy, and utility of endovascular treatment for delayed PPH

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