Abstract
The gap between the growing demand for available organs and the cadaveric organs facilitates the adoption of living donor liver transplantation. We retrospectively identified and evaluated the post-operative complications as per the modified Clavien classification system in 152 living liver donors at at the First Affiliated Hospital, College of Medicine, Zhejiang University between December, 2006 and June, 2014. Post-operative complications were observed in 61 patients (40.1%) in the present study, but no mortality was reported. Complications developed in 58 (40.0%) right, 1 (33.3%) left, and 2 (66.7%) lateral left hepatectomy donors. The prevalence of re-operation was 1.3%. Grade I and II complications were observed in 38 (25.0%) and 11 (7.2%) donors, respectively. Grade IIIa complications developed in 9 (5.9%) donors and only 3 (2.0%) patients reported grade IIIb complications. The most common complication was pleural effusion that occurred in 31 (20.4%) donors. No significant prognostic baseline factor was identified in this study. In conclusion, living donors experienced various complications, which were usually mild and had a good prognosis.
Highlights
Liver transplantation (LTx) is probably the only treatment strategy in patients with terminal liver diseases
The in-hospital and follow-up data was acquired from the patient records and the China Liver Transplant Registry, which was authorized as the only National liver transplantation registry in Mainland China by the Ministry of Health in May 2008
Donor safety is the prime priority associated with Living-Donor Liver Transplantation (LDLT) procedure
Summary
Liver transplantation (LTx) is probably the only treatment strategy in patients with terminal liver diseases. Despite the tremendously growing demand for available organs and mortality of the waiting list, the amount of grafts available is low. This disparity facilitates a more open acceptance of livers procured from other channels, including Living-Donor Liver Transplantation (LDLT). As an alternative of cadaveric liver transplantation, LDLT was first attempted in 1988 [1] and was successfully performed in 1990 [2] Several advantages, such as shorter waiting time, no warm ischemia time, and diminished cold ischemia time [3], make LDLT an ideal solution, especially when no other grafts are available and the surgery is urgent. Since the adoption of the right lobe liver for LDLT [4], concerns about a perfectly healthy donor receiving a PLOS ONE | DOI:10.1371/journal.pone.0135557 August 13, 2015
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
