Abstract

Leg swelling after menopause is common. The prevailing concept in primary care is that it is polycentric and a treatable cause may not be found. Traditional systemic causes may be investigated, but venous etiology is rarely considered. Patients are prescribed empiric diuretics, often without benefit. Our clinical experience indicates that iliac venous vein obstruction is frequently the core cause. A variety of secondary factors that are common in the postmenopausal life stage (eg, joint surgery, onset of venous reflux, venosclerosis, seated orthostasis) disturb the precarious regional fluid balance and precipitate swelling.

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