Abstract
Abstract We report on the case of a 40-year-old male who was admitted to the clinic with a large ulcer on his left buttock, 3 days after an intramuscular benzathine penicillin injection. The patient was diagnosed with Nicolau syndrome, a rare vascular complication in which a lesion develops after intramuscular injection. Symptoms are intense pain at the injection site, erythema, and livedoid dermatitis, which leads to necrosis of skin, subcutaneous tissue and muscle tissue. It was described by Nicolau after intramuscular injections of bismuth salt for syphillis therapy. Nicolau syndrome is rare, but its symptoms are devastating and healthcare professionals must be aware of this clinical entity, since intramuscular injections are common procedures for administration of drugs.
Highlights
CASE REPORTPost-injection embolia cutis medicamentosa – Nicolau Syndrome: case report and literature review
Intramuscular injections for administering drugs are common procedures because they are effective and offer rapid response times.[1]
Nicolau syndrome presents with pain at the site of injection immediately after drug administration, followed by hyperemia, skin discoloration, abscess formation, and ischemic necrosis and severe cases can even lead to death.[1,4,5]
Summary
Post-injection embolia cutis medicamentosa – Nicolau Syndrome: case report and literature review. Carlos Alberto Araujo Chagas[1], Tulio Fabiano de Oliveira Leite[2], Lucas Alves Sarmento Pires1 *
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