Post-exposure human rabies prophylaxis: spatial patterns of inadequate procedures in Ceará - Brazil, 2007 to 2015.

Kellyn Kessiene De Sousa Cavalcante,Carlos Henrique Alencar,Caroline Mary Gurgel Dias Florêncio,Francisco Gustavo Silveira Correia,Jarier De Oliveira Moreno

doi:10.1590/0037-8682-0247-2019

Kellyn Kessiene De Sousa Cavalcante, Carlos Henrique Alencar + Show 3 more

Open Access

https://doi.org/10.1590/0037-8682-0247-2019

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Abstract

INTRODUCTION: This study investigated the spatial distribution of inappropriate post-exposure human rabies procedures in Ceará, Brazil, between 2007 and 2015. METHODS: The ecological study population was based on the records of post-exposure human rabies procedures from the Notification Disease Information System. We analyzed the data using the Moran Index (I) and the Moran Local Index. RESULTS: There were 222,036 (95.8%) records with inappropriate post-exposure human rabies procedures. There was heterogeneity in their spatial distribution, with two significant clusters in the northeast and northwest regions. CONCLUSIONS: These findings help elaborate differentiated strategies to reduce unnecessary post-exposure human rabies procedures.

Highlights

This study investigated the spatial distribution of inappropriate post-exposure human rabies procedures in Ceará, Brazil, between 2007 and 2015
Considering the importance of the epidemiology of rabies prophylaxis, this study aimed to characterize the spatial distribution of inappropriate post-exposure human rabies procedures from 2007 to 2015 in Ceará, Brazil
Procedures that did not follow the protocol of the Brazilian Ministry of Health, or presented incomplete data were found to be inadequate, either due to an absence or an excess of treatment[3,5,9]

Summary

Introduction

This study investigated the spatial distribution of inappropriate post-exposure human rabies procedures in Ceará, Brazil, between 2007 and 2015. Considering the importance of the epidemiology of rabies prophylaxis, this study aimed to characterize the spatial distribution of inappropriate post-exposure human rabies procedures from 2007 to 2015 in Ceará, Brazil. Procedures that did not follow the protocol of the Brazilian Ministry of Health, or presented incomplete data were found to be inadequate, either due to an absence or an excess of treatment[3,5,9].

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