Abstract
Post Exercise Desaturation Can Help Identifying Treatment Responders of COPD Pulmonary Hypertension in Real World: An Appraisal
Highlights
Chronic Obstructive Pulmonary Disease (COPD) is a common airway disease and is a growing public health problem [1]
Inference: Patients of COPD associated pulmonary hypertension (COPD-pulmonary hypertension (PH)) treated on the basis of exercise desaturation showed significant improvement to PH specific pharmacotherapy
The observation demands attention and validation to define the indication of PH specific pharmacotherapy in COPD-PH
Summary
COPD is a common airway disease and is a growing public health problem [1]. By 2020, it is predicted to be the third leading cause of death [2,3]. The prevalence of PH in COPD has been reportedly to be approximately 30%-70% [5] The majority of this problem is encountered in advanced COPD patients with mild to moderate increase in pulmonary artery pressure (PAP) and is referred to as COPD-PH. While the guidelines are categorically instructive regarding administering PH-specific treatment in PH-COPD patients, they are silent regarding the majority (COPD-PH cases) possibly for lack of high quality evidence to define pharmacotherapy in them. This lack of directives in guidelines might have led to a deterrent effect on decision for PH specific pharmacotherapy by a physician for COPD-PH. COPD associated pulmonary hypertension (COPD-PH) leads to desaturation on exercise It affects the health status and survival adversely
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