Abstract
99mTc eluate in 0.7/0.35M acetic acid and in 1:1v/v 0.7M acetic acid: 0.025M ammonium acetate (30–40ml) was conveniently concentrated by passing through a small column of a readily available weak anion exchanger, DEAE cellulose, (200mg, 6×8mm) and subsequent elution with 3ml normal saline, with greater than 90% recovery. The quality of pertechnetate thus obtained and its compatibility for preparing 99mTc compounds were satisfactory. This method was successfully applied to the alumina column chromatographic generator produced in-house and to a commercial 99Mo–99mTc generator after extensive clinical use. Potential for much higher concentration factors with compacted anion exchanger cartridges as well as applicability for 188W–188Re generator are discussed.
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