Abstract

Both theoretical considerations and in vitro studies indicate that the rate of absorption of ionic drugs may be enhanced by use of polyelectrolytes. It is shown that the rate of transfer of substances such as sodium salicylate, and potassium benzyl penicillin through cellophane membranes is materially increased by presence of such polyelectrolytes, as sodium carboxymethylcellulose, sodium polyacrylate, and others.

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