Abstract
Plasma levels of IgA, IgG and IgM have been measured in 35 British and 37 Japanese normal adult women, in 22 British and 22 Japanese adolescent girls and in 30 Japanese women with breast cancer. Japanese women had significantly higher blood concentrations of IgG and IgM than British women. The amounts of plasma immunoglobulins in adolescent British and Japanese girls were similar to those in adults of the same race, except for IgG, where Japanese adolescent girls had significantly lower levels than in adult Japanese women. In contrast to previous results showing no difference between the IgA, IgG and IgM levels of normal British women and patients with breast cancer, the IgM concentration was significantly lower in the Japanese patients compared with that in Japanese controls.
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