Possible Relation of Skin and Nail Changes in an Infant to COVID-19 Infection

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first reported in China in December 2019, rapidly developed into a global pandemic and public health emergency. A variety of cutaneous manifestations associated with coronavirus disease 2019 (COVID-19) have been described in the literature, including urticarial, maculopapular, papulovesicular, purpuric eruptions, livedo reticularis, and thrombotic ischemic lesions. COVID toes, or acute COVID-19-associated chilblains, have been reported as a manifestation of COVID-19 in teenagers and children, as young as 5 years old. We are presenting a case of an 11-month-old female who presented to our clinic with two distinct skin changes following COVID-19 infection: one, COVID-19-related toes, fingers, and nails, and two, exacerbation of atopic dermatitis secondary to COVID-19. To our knowledge, this is the first case of skin and nail manifestation in an infant following COVID-19 infection. This case also supports the current literature that atopic dermatitis can be triggered by COVID-19 infection in predisposed individuals. Int J Clin Pediatr. 2022;11(2):39-44 doi: https://doi.org/10.14740/ijcp481