Abstract
Powassan virus (POWV) encephalitis is a rare tickborne illness. We describe the clinical course, laboratory findings, and imaging for a patient with POWV in Massachusetts, USA. Clinical presentation and laboratory findings were nonspecific. Improvement on brain magnetic resonance imaging after 2 weeks preceded clinical improvement by months, suggesting possible prognostic value.
Highlights
Powassan virus (POWV) encephalitis is a rare tickborne illness
We describe the clinical course of POWV encephalitis in a man living in Massachusetts
Magnetic resonance imaging (MRI) of the brain of a patient with encephalitis caused by Powassan virus, Massachusetts, USA, 2017
Summary
Magnetic resonance imaging (MRI) of the brain of a patient with encephalitis caused by Powassan virus, Massachusetts, USA, 2017. A) Initial brain MRI showing high T2 signal abnormality in the bilateral caudate and putamen. B) Noticeable improvement on repeat brain MRI 2 weeks later. POWV-specific IgM and plaque reduction neutralization tests of the CSF and serum (performed at CDC) confirmed infection. Five months after initial hospitalization, the patient returned to the neurologist, who reported that the patient’s mental status had returned to baseline
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