Abstract
We observed that patients with a variety of metabolic bone diseases had elevated fractions of bone alkaline phosphatase as determined by polyacrylamide disc electrophoresis and thermostability studies. We undertook an epidemiologic investigation to determine if there is any causal relationship between increased bone alkaline phosphatase in the perimenopausal healthy woman and later development of osteoporosis as reflected in bone fractures. The results after an 8-year follow-up show that the fracture rate in the normal group was statistically significantly lower than the fracture rate in the elevated group after adjustment for chronologic and postmenopausal ages (p = 0.05).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
