Abstract
https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000018556, UMIN000015953.
Highlights
Schizophrenia patients elicit psychotic symptoms, mood symptoms, and cognitive impairment [1,2,3]
This study was the first to suggest the ability of transcranial direct current stimulation (tDCS) to improve daily living skills linked to cognition, as well as depressive symptoms in patients with schizophrenia
This study was the first to indicate the improvement of functional capacity after 5-day administration of tDCS, which was not correlated with the change of cognition, psychosis, and depression
Summary
Schizophrenia patients elicit psychotic symptoms, mood symptoms, and cognitive impairment [1,2,3]. Real-world functional outcomes (social function) are greatly affected by several factors, such as opportunities and incentives tDCS and Functional Outcomes that influence functioning in everyday situations [7]. These levels of functional outcomes (cognitive function, functional capacity, social function) have been reported to be associated with each other [8, 9]. TDCS changes cortical excitability, modulated by glutamatergic activity via actions on catecholamine, acetylcholine and serotonin receptors [17,18,19] With this mechanism, tDCS over the left DLPFC has been suggested to modulate corticosubcortical/corticocortical pathways [20, 21]
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