Abstract
Abstract To achieve the ultimate goal in “individualizing” drug samples, qualitative and quantitative composition determinations are commonly used [1–5]. Based on quantitative analysis of major cannabinoids, pharmaceutical scientists [2,3] have concluded that Cannabis sativa L. can be chemically categorized into drug and fiber types. These investigators [2,3] further established that the phenotype of a plant is determined by the genetic origin of the seed, and the location of cultivation is irrelevant. On the other hand, according to geochemists, environmental factors seem to control isotope distribution in plants of the same species. Although the category of a plant is controlled by the adopted carbon fixation pathway [6–8], the carbon isotope ratio 13C/12C within a category reflects the environmental conditions such as humidity, temperature, photoperiod, and isotope composition of ambient carbon dioxide [7–14] in which the plant has grown. It is therefore interesting to analyze the isotopic distribution in Cannabis sativa L. of different origins grown under various conditions for possible characterization of seed origin and location of cultivation.
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