Abstract
Background: The present study was conducted to evaluate the protective role of pomegranate juice alone or in
 combination with propolis extract against isoproterenol (ISO) induced myocardial infarction in rats.
 Material and Methods: Male Wister albino rats (n=60) weighing 220-280 g were divided into six groups each group
 contain ten rats; group I: negative control fed standard diet. Group (II-VI): Rats were injected subcutaneously with
 isoproterenol (150 mg/kg) for 3 days. Group III: Rats were given pomegranate juice 1ml /rat / day. Group IV: Rats
 were given propolis extract (50 mg/kg BW). Group V: Rats were given pomegranate juice + propolis extract. Group
 VI: Rats were given glyceronitrate (2.6mg/kg.bw/day).
 Results: The ISO-induced myocardial infarction in untreated rats has indicated by significant (p < 0.001) elevation of
 cardiac marker enzymes such as aspartate aminotransferase (AST), Lactate dehydrogenase (LDH), creatine kinase
 (CK), and cardiac troponin I (CnI ) when compared with control group. Rats treated with pomegranate juice and
 propolis extracts showed highly significant (p
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