Possibilities of PET/CT with 18F-PSMA-1007 in the Diagnosis of Triple Negative Breast Cancer: a Case Study

Abstract

Breast cancer (BC) is one of the most common cancers and the leading cause of cancer death in women. Triple negative breast cancer (TNBC) is a specific subtype of breast cancer that does not express estrogen receptors (ER), progesterone receptors (RP) or human epidermal growth factor receptor-2 (HER-2), has certain clinical features, a tendency to relapses and poor prognosis. Various studies demonstrate that prostate-specific antigen (PSA) is not strictly specific for prostate cancer, and can be produced by other tumor pathologies. In routine practice, PET/CT for TNBC is performed with 18F-FDG. However PET/CT with 18F-PSMA-1007 can be used as the method of choice with high theranostic potential. Here is a clinical case of a patient with TNBC who underwent PET/CT with 18F-FDG and 18F-PSMA-1007.