Possibilities of non-drug treatment methods in the correction of dyslipidemia and manifestations of individual components of the metabolic syndrome

Abstract

Aim of the study was to identify the place of low-intensity electro-pulse therapy with biofeedback when it is included in the rehabilitation complex of patients with abdominal obesity to correct the quality of life and individual components of the metabolic syndrome.Material and methods. In the conditions of the outpatient diagnostic center of City Clinical Hospital No. 2 of Novosibirsk, 60 men and women with abdominal obesity, arterial hypertension and insulin resistance were examined, divided into 3 groups: 1st (main group, n = 25) in addition for standard therapy received a 15-day course of dynamic electroneurostimulation (DENS) from the Neurodance-PCM device; the 2nd (comparison group 1, n = 20), in addition to the basic complex, received DENS procedures from a placebo device, the 3rd (comparison group 2, n = 15) was treated with the use of only a basic therapeutic complex. The control group included 17 men and women without clinical manifestations from the endocrine and cardiovascular systems. The examination included examinations by an endocrinologist, a nutritionist, anthropometry and bioimpedance, assessment of quality of life parameters.Results. In group 1 patients, 1 month after the start of rehabilitation, there was a greater tendency than in the comparison groups to decrease the body mass index by 9.0 %, a correction of the percentage content in the body structure of fat mass by 1.4 times (p = 0.029) occurred, preprandial glycemia decreased by 1.4 times (p = 0.043) and the level of triglycerides in the blood serum – by 1.4 times (p = 0.044), the increased concentration of free leptin and resistin decreased (1.2 times, p = 0.039), the content of adiponectin in the blood serum increased by 1.2 times (p = 0.041), the quality of life improved 1 month after the start of rehabilitation according to the components of physical and psychological health, which is not observed in the placebo and standard treatment groups.Conclusions. The inclusion of DENS from the Neurodance-PCM device in the comprehensive rehabilitation of patients with abdominal obesity can contribute to the correction of anthropometry, bioimpedance, carbohydrate and adipokine metabolism indicators. This makes it possible to recommend the inclusion of low-intensity electro-pulse therapy in complex rehabilitation for the correction of quality of life indicators and individual components of the metabolic syndrome.