Abstract
The conducted research and own observations demonstrated the current possibilities for verification of neonatal sepsis in newborns. In both clinical cases, neonatal sepsis has developed in premature infants born from mothers having infectious risk factors in their anamnesis. The peculiarities of clinical manifestations were a rapid increase in the phenomena of multiple organ failure with the damage of a number of organs and systems, thrombocytopenia and leukocytosis, high level of C-reactive protein, and presepsin rate. In the epidemiological respect the associations of microorganisms prevailed among the pathogens, in particular, antibiotic resistant strains of Klebsiella pneumonia in combination with Ac. Baumannii and St. Epedermidis took the leading place among them. It has been shown that the determination of the presepsin rate in biological media is perspective for the early and reliable verification of neonatal sepsis, especially among premature infants.
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