Positive scintigraphy of tumor by means of intra-arterial injection of radioiodinated macroaggregated albumin (MAA).

Abstract

Selective arterial catheterization by Seldinger's technique was performed in 52 cases, apart from 3 cases of carotid artery puncture, followed by injection of radio-iodinated (I131- or I125-) MAA in doses of 250-500 µc (1-5 mc of higher specific activity) into the arteries through the catheter or needle.Serial scintigraphy was made daily until the tumor became positively delineated from the surrounding normal tissue or for at least 2 weeks if this did not occur.In most of the cases of tumor, a positive scintigram was obtained. Non-neoplastic cases were essentially negative. Surgically[See figure in the pdf file]removed specimens contained higher radioactivity in the neoplastic tissues than in the normal or non-neoplastic tissues.