Abstract

We aimed to investigate the potential and mechanism of probiotics as digestive enzyme inhibitors to alleviate nonalcoholic fatty liver disease (NAFLD). We compared the level of NAFLD in rats before and after Limosilactobacillus plantarum grx16 intervention, as well as changes in gut digestive enzymes and inflammatory factors. L. plantarum grx16 inhibited the absorption of starch and triglycerides by inhibiting the activity of gut amylase and lipase to alleviate insulin resistance and reduce lipid accumulation in the body, thereby alleviating the inflammatory response, and thus alleviating NAFLD in rats.

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