Positional flexibilities of amino acid residues in globular proteins

Abstract

The fluctuational amplitudes of the amino acid residues in 19 protein molecules are computed by the use of our differential equation model and are analysed statistically to get new information as to their stability, position dependent nature, distribution and group dynamical behaviour, etc. The symmetric/asymmetric distribution of amino acid residues in the protein molecules is described by introducing a parameter called the “flexibility index” for each of the residue types. Finally, the overall flexible nature of the amino acid residues with respect to their spatial positioning is explained and their relationships with the residue properties are derived.