Posibila asociere dintre diabetul zaharat de tip 2 şi tiroidita autoimună Hashimoto – rezultate finale

Abstract

Introduction. The idea for our clinical research came from the association between type 2 diabetes and autoimmune thyroiditis that we often see in our daily practice. We wanted to study this to see if it is only a coincidence or if indeed this association really exists. Method. We created an observational retrospective research using 5,064 patients with type 2 diabetes, patients from Sanamed Hospital, which came at site between January 2016 and December 2018. Out of the large group of patients, we created 3 secondary groups: one containing 50 patients with type 2 diabetes, one with 50 patients with autoimmune thyroiditis and one with 50 patients which had both diseases. We initially evalueted the large group and after that we studied the 3 smaller groups. Results. We were able to prove the main hypothesis of our study by showing that the incidence of thyroiditis was significantly higher in the population with type 2 diabetes from our main group, the 5,064 patients, in contrast with the incidence that thyroiditis has in the healthy population from Europe. In our study we also demonstrated that the association between this 2 diseases has a protective role in regards with the incidence of obesity, arterial hypertension, dyslipidemia and macrovascular complications of the type 2 diabetes. Also, we found out that in the case of this association there are significant differences for a serial of biochemical parameters as well, such as blood glucose, uric acid, elements of the lipid profile. Discussions. The results from our study were consistent with the results form other international studies regarding this topic. This finding led us to the conclusion that our initial observation, that this two conditions might be associated, was not only a coincidence, but it is a definite association proved by us in this study. Conclusions. We proved our initial hypothesis to be true by the significant difference in incidence of thyroiditis in the population of our study in comparison with the incidence of thyroiditis in the healthy European population. We also managed to prove the secondary hypothesis to be correct.