Abstract

Multiple or single inhaler triple therapy (MITT, SITT) comprising ICS+LABA+LAMA is used for asthma and COPD. Algorithms to identify MITT use in real-world databases were developed for COPD patients and may not be appropriate for asthma patients (who should use two inhalers, a fixed combination of ICS-LABA, plus LAMA). We explored key algorithm assumptions by making small changes to these and observing the impact on estimates of MITT prevalence and MITT adherence.

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