Abstract

Stroke is associated with high risk of mortality and recurrent cardiovascular events, with risk increasing for people with comorbidities. Rehabilitation is critical for improving functional recovery, and was shown to reduce hospital readmissions, as well as all-cause and cardiovascular mortality and stroke recurrence (long-term outcomes), but spasticity (occurring in 30% of stroke survivors) may prevent effective recovery. AbobotulinumtoxinA (ABoNTA) is an established treatment for post-stroke spasticity (PSS), but its impact on long-term outcomes is unknown.

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