Abstract
Cardiovascular disease (CVD) has consistently remained the leading cause of morbidity and mortality in end-stage renal disease (ESRD) patients. Although hyperoxalemia is a well-known feature in ESRD patients, the clinical data on association between plasma oxalic acid (POx) concentration and cardiovascular outcomes in the dialysis population has never been analyzed before. It was hypothesized that oxalate might be strongly involved in atherogenesis and the inflammatory pathway that could result in an increased risk of CVD in ESRD patients.Therefore, this study aimed to evaluate the potential role of elevated POx concentration in the development of cardiovascular risk in ESRD patients.
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