POS1409 NEW INSIGHTS INTO THE ANTIPHOSPHOLIPID SYNDROME SPECTRUM: FROM ANTIPHOSPHOLIPID ANTIBODIES POSITIVE SUBJECTS PROFILING TO IDENTIFICATION OF SYSTEMIC APS SUBSET THROUGH TYPE I INTERFERON PATHWAY ACTIVATION

Abstract

BackgroundType I Interferon (IFN) pathway activation plays a central role in the pathogenesis of several autoimmune conditions. However, limited evidence is available on the IFN pathway activation in antiphospholipid antibody...