POS1332 ANTI-NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE AUTOANTIBODIES ARE ASSOCIATED WITH A NEW CLINICAL PHENOTYPE IN SYSTEMIC SCLEROSIS PATIENTS: LIMITED CUTANEOUS SUBSET WITH RECALCITRANT CALCINOSIS AND HIGHER RISK OF CANCER

Abstract

BackgroundIt has been reported that 80-85% of established systemic sclerosis (SSc) patients present anti-nuclear autoantibodies (ANAs) [1]. However, in a group of clinically heterogeneous patients with high-titer ANAs no SSc-specific...