POS0330 SYNOVIAL M1 MACROPHAGES AND FIBROBLASTS DUAL-TARGETING LIPOSOMES ASSISTED DELIVERY OF TRIAMCINOLONE ACETONIDE IS EFFECTIVE AGAINST JOINT PAIN AND CARTILAGE DEGENERATION IN OSTEOARTHRITIS

Abstract

BackgroundThe latest professional guidelines recommend intra-articular (IA) glucocorticoids (GCs) for pain relief in patients with knee osteoarthritis (OA). However, their effect is small-to-moderate and short-term only[1]. There is also concern...