POS-784 VESICO-URETERAL REFLUX POST RENAL TRANSPLANTATION,A DESCRIPTIVE STUDY

Abstract

The vesico-ureteral reflux (VUR) is a urological complication frequently encountered in post renal transplantation (RT), reaching 10 to 15% in some series. The objective of our study is to determine the prevalence of VUR after RT, to study the characteristics of the affected population and the impact on graft function. A retrospective descriptive study of all kidney transplant patients between 2007 and 2018 who were diagnosed with a VUR after RT. The characteristics of the initial nephropathy, the mode of revealing of the reflux, the consequences on renal function and the recurrence of urinary tract infections were studied for each . Among the 209 kidney transplants, 31 patients had a RVU, making it a prevalence of 14,8 %, with a sex ratio of 1,58 : 19 men and 12 women. The mean age at the time of transplantation was 28,33 years old. For initial nephropathy, 22 had chronic interstitial nephropathy (71%) including 8 secondary to reflux nephropathy, 19,4% had a glomerular desease and 3,2 % had a vascular cause. Before transplantation, patients had an average hemodialysis duration of 2.6 years with extremes ranging from a few months to 10 years, 13 patients were already oligo-anuric. As for VUR on graft, it was diagnosed with an average delay of 11.5 months post TR [3 months;36months] in front of recurrent urinary tract infections in 10 patients, pyelocalicial dilation seen on renal ultrasound in 4 cases and unexplained creatinine increase in 6 cases. VUR on renal graft is seen in patients of different sex and age with a variable duration of hemodialysis and residual diuresis, but in post-transplantation, it is the recurrence of urinary tract infections that should make the diagnosis suspected.