Abstract
Chronic kidney disease leads to cumulative vascular damage that increases aortic stiffness, which is an independent predictor of cardiovascular events. Analysis of Digital Volume Pulse recordings has been proposed to assess arterial stiffness. It is proposed that the systolic peak timing (T1) represents the forward-travelling pressure from the ventricle, and the peak diastolic component (T2) arises mainly from the reflected wave pressures from the lower parts of the body. Hence, using height of a subject and the transit time, one could calculate a pulse wave velocity and estimate arterial stiffness.
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